diff --git a/pxr/usd/usdMtlx/reader.cpp b/pxr/usd/usdMtlx/reader.cpp
index 29e901816..e6fc68b20 100644
--- a/pxr/usd/usdMtlx/reader.cpp
+++ b/pxr/usd/usdMtlx/reader.cpp
@@ -797,6 +797,15 @@ _NodeGraphBuilder::_CreateInterfaceInputs(
     // We deliberately ignore tokens here.
 }
 
+mx::StringSet _GetStdlibIncludes() {
+    mx::StringSet stdlibIncludes = UsdMtlxGetDocument("")->getReferencedSourceUris();
+    mx::StringSet normStdlibIncludes;
+    for (std::string const& entry : stdlibIncludes) {
+        normStdlibIncludes.insert(TfNormPath(entry));
+    }
+    return normStdlibIncludes;
+}
+
 // Returns True if the mtlxNodeDef corresponds to a locally defined custom node
 // with an associated nodegraph.
 // XXX Locally defined custom nodes without nodegraphs are not supported
@@ -818,13 +827,14 @@ _NodeGraphBuilder::_IsLocalCustomNode(const mx::ConstNodeDefPtr &mtlxNodeDef)
         }
         // Combine with the nodeDef relative path
         nodeDefUri = TfNormPath(fullMtlxPath + nodeDefUri);
+    } else {
+        nodeDefUri = TfNormPath(nodeDefUri);
     }
     
     // This is a locally defined custom node if the absolute path to the
     // nodedef is not included in the stdlibDoc.
     static mx::StringSet customNodeDefNames;
-    static const mx::StringSet stdlibIncludes =
-        UsdMtlxGetDocument("")->getReferencedSourceUris();
+    static const mx::StringSet stdlibIncludes = _GetStdlibIncludes();
     if (stdlibIncludes.find(nodeDefUri) == stdlibIncludes.end()) {
         // Check if we already used this custom node
         if (std::find(customNodeDefNames.begin(), customNodeDefNames.end(),